The EPS 16 works exactly the same as an ASR, its just stripped down in some ways (though it does have advantages in others). The 16 Plus samples in mono rather than stereo, has more available sample rates than the ASR (and can sample at a higher sample rate than the ASR can), and has less effects. It also has the Turbo option available so you don't have to boot from floppy (I have this on my rackmount), the ASR never got this option.
I have also found it to be more stable than the later iterations of the ASR OS because they tried to put so much stuff in it. The ASR gives a lot of error 44's and crashes while the EPS has a leaner/more stable OS. The 16 plus only ever crashed on me once. You might get random pauses while it says shuffling data or whatever but it'll come back eventually.
They are beautiful sounding samplers. I have an OG EPS keyboard, one 16 plus keyboard and a rackmount, 2 ASR keyboards and 2 rackmounts, and 2 ASR X's. They are my favorite sampler series of all time along with the SP 1200. It took me a while to get my head around the routing and architecture, but when you do, I'd have to use a DAW to rival what they can do as far as stacking sounds and mangling them.
The ASR has a little more bass, but the 16 plus has a nice high end, especially on drums. True Master is a great example of what the EPS 16 Plus can sound like when you sample at a low sample rate and play your sounds with the keys. Also, cats give the sequencer a bad name. No, it doesn't have the automatic swing an old MPC does, but you can dial it in and its dead simple to use.
This guys channel is essential, I learned tons of stuff from him. I've owned an ASR over a decade and I'm still learning new tricks.
When I found out you can adjust your start and end points using the modwheel and play out chops with the keyboard with start/end adjusted via modulation
Sidenote: buy an OEX6 or OEX6SR if you can find one at a resonable price. They are expensive as hell now and it sucks tracking your beats out without one.