1/35
@vitrupo
Mindblowing demo: John Link led a team of AI agents to discover a forever-chemical-free immersion coolant using Microsoft Discovery.
The agents surfaced a material "unknown to humans" — in hours, not months — and the team synthesized it in the lab.
"It's literally very cool."
https://video.twimg.com/amplify_video/1924561587853225984/vid/avc1/1024x768/CHRb5svz5aduYFz4.mp4
2/35
@vitrupo
Microsoft Chemisty Product Lead John Link at Microsoft Build:
3/35
@vitrupo
Microsoft Discovery is a new enterprise agentic platform to accelerate research & development.
"Our goal is to bring the power of AI to scientists and engineers to transform the entire discovery process—from advanced knowledge reasoning and hypothesis formulation to experimental simulation and iterative learning. Microsoft Discovery enables researchers to collaborate with a team of specialized AI agents combined with a graph-based knowledge engine, to drive scientific outcomes with speed, scale, and accuracy."
Official blog post: Transforming R&D with agentic AI: Introducing Microsoft Discovery | Microsoft Azure Blog
4/35
@DoctorLex
@grok what does it mean forever chemical free in respect to immersion coolant. Is this new coolant cheap enough to be used in real world applications?
5/35
@grok
"Forever chemical free" means the immersion coolant lacks PFAS, synthetic chemicals that persist in the environment and pose health risks. PFAS-free coolants are more eco-friendly, aligning with regulations like EPA's hazardous substance designation and potential EU bans by 2025. The new coolant's cost isn't public, but PFAS-free alternatives often start pricier due to R&D, though long-term costs may drop with scale. Compared to PFAS-based coolants like 3M's Novec, which are phasing out, cost-effectiveness is unclear without specific data. Industry trends suggest PFAS-free options could become competitive as regulations tighten.
6/35
@Excel4Freelance
Insane how fast AI is accelerating discovery
I’ve been using AI myself to help build smarter Excel VBA apps—cuts dev time and boosts creativity in ways that weren’t possible before. This is just the beginning.
7/35
@theonejvo
The amount of water he needed to do those "intense computations"
8/35
@Shawnryan96
Straight amazing I have watched it 3 times now
9/35
@wolfthehunter
10/35
@amol_sri1
@itsTarH
11/35
@Nighttrekker3
That's incredible, wow!
12/35
@DavidLazarusK
So can we use it?
13/35
@vitrupo
It's an enterprise product for now and they do have a sign up form for private previews: Accelerating Scientific Discovery Private Preview
14/35
@SacrificialAlly
Aw, he's doin a me.
15/35
@Bunagayafrost
solid innovator example
16/35
@hzdydx9
This is next-level innovation.
17/35
@ImCaptdan
Lit
18/35
@philliplanos
Woah….
19/35
@robotelier
awesome
20/35
@bowtiedwhitebat
we wil get cheap eenrgy andfree food aint
21/35
@Gdgtify
seriously impressive.
22/35
@purepathwill
This is why AGI is worth all the current investment and more.
23/35
@the_photino
We are going to see more and more of this in the comming months
24/35
@Agm1340703Agm
The X post by
@vitrupo
highlights a significant advancement in AI-driven scientific discovery, where Microsoft Discovery, an enterprise agentic platform, enabled a team led by John Link to identify a new material for a PFAS-free immersion coolant in just hours, a process that traditionally could take months or years.
This breakthrough involved AI agents collaborating to surface a material "unknown to humans," which was then synthesized and tested in a lab, demonstrating its effectiveness in maintaining stable temperatures without fans, thus showcasing the potential of AI to accelerate and transform scientific research.
The context of this achievement is underscored by Microsoft's broader initiative at Build 2025 to leverage AI for scientific outcomes, as part of a shift towards discovery engines that not only find new materials but also consider ethical implications, aligning with the evolving role of AI in fields like chemistry and materials science.
25/35
@ferrants
Is Microsoft killing it?
26/35
@Heavensshiranui
Amazing, this is becoming increasingly common, and this is the worst it ill ever be!
27/35
@rediminds
Labs used to chase molecules; now molecules chase us. What matters next isn’t speed, it’s having the guardrails to prove a “machine-discovered” material is safe, compliant, and manufacturable at scale. Hats off to John Link and the team for showing that AI acceleration can coexist with real-world validation.
28/35
@ayushjha__
Really cool stuff, We have been using it for materials
29/35
@AntDX316
The ASI-Singularity(Godsend) is the only Global Solution.
30/35
@justinwcaswell
For the record and before Netflix or Disney fukk it up…this is a white male.
31/35
@mikeamark
Using Microsoft discovery, AI is helping to make scientific discoveries.
32/35
@reyreyromonov
33/35
@AGuyNamedDJ_
I’m not cracked enough
34/35
@msakiart
wow impressive
35/35
@HeiligGerh36381
Wow
To post tweets in this format, more info here: https://www.thecoli.com/threads/tips-and-tricks-for-posting-the-coli-megathread.984734/post-52211196
@vitrupo
Mindblowing demo: John Link led a team of AI agents to discover a forever-chemical-free immersion coolant using Microsoft Discovery.
The agents surfaced a material "unknown to humans" — in hours, not months — and the team synthesized it in the lab.
"It's literally very cool."
https://video.twimg.com/amplify_video/1924561587853225984/vid/avc1/1024x768/CHRb5svz5aduYFz4.mp4
2/35
@vitrupo
Microsoft Chemisty Product Lead John Link at Microsoft Build:
3/35
@vitrupo
Microsoft Discovery is a new enterprise agentic platform to accelerate research & development.
"Our goal is to bring the power of AI to scientists and engineers to transform the entire discovery process—from advanced knowledge reasoning and hypothesis formulation to experimental simulation and iterative learning. Microsoft Discovery enables researchers to collaborate with a team of specialized AI agents combined with a graph-based knowledge engine, to drive scientific outcomes with speed, scale, and accuracy."
Official blog post: Transforming R&D with agentic AI: Introducing Microsoft Discovery | Microsoft Azure Blog
4/35
@DoctorLex
@grok what does it mean forever chemical free in respect to immersion coolant. Is this new coolant cheap enough to be used in real world applications?
5/35
@grok
"Forever chemical free" means the immersion coolant lacks PFAS, synthetic chemicals that persist in the environment and pose health risks. PFAS-free coolants are more eco-friendly, aligning with regulations like EPA's hazardous substance designation and potential EU bans by 2025. The new coolant's cost isn't public, but PFAS-free alternatives often start pricier due to R&D, though long-term costs may drop with scale. Compared to PFAS-based coolants like 3M's Novec, which are phasing out, cost-effectiveness is unclear without specific data. Industry trends suggest PFAS-free options could become competitive as regulations tighten.
6/35
@Excel4Freelance
Insane how fast AI is accelerating discovery
I’ve been using AI myself to help build smarter Excel VBA apps—cuts dev time and boosts creativity in ways that weren’t possible before. This is just the beginning.7/35
@theonejvo
The amount of water he needed to do those "intense computations"
8/35
@Shawnryan96
Straight amazing I have watched it 3 times now
9/35
@wolfthehunter
10/35
@amol_sri1
@itsTarH
11/35
@Nighttrekker3
That's incredible, wow!
12/35
@DavidLazarusK
So can we use it?
13/35
@vitrupo
It's an enterprise product for now and they do have a sign up form for private previews: Accelerating Scientific Discovery Private Preview
14/35
@SacrificialAlly
Aw, he's doin a me.
15/35
@Bunagayafrost
solid innovator example
16/35
@hzdydx9
This is next-level innovation.
17/35
@ImCaptdan
Lit
18/35
@philliplanos
Woah….
19/35
@robotelier
awesome
20/35
@bowtiedwhitebat
we wil get cheap eenrgy andfree food aint
21/35
@Gdgtify
seriously impressive.
22/35
@purepathwill
This is why AGI is worth all the current investment and more.
23/35
@the_photino
We are going to see more and more of this in the comming months
24/35
@Agm1340703Agm
The X post by
@vitrupo
highlights a significant advancement in AI-driven scientific discovery, where Microsoft Discovery, an enterprise agentic platform, enabled a team led by John Link to identify a new material for a PFAS-free immersion coolant in just hours, a process that traditionally could take months or years.
This breakthrough involved AI agents collaborating to surface a material "unknown to humans," which was then synthesized and tested in a lab, demonstrating its effectiveness in maintaining stable temperatures without fans, thus showcasing the potential of AI to accelerate and transform scientific research.
The context of this achievement is underscored by Microsoft's broader initiative at Build 2025 to leverage AI for scientific outcomes, as part of a shift towards discovery engines that not only find new materials but also consider ethical implications, aligning with the evolving role of AI in fields like chemistry and materials science.
25/35
@ferrants
Is Microsoft killing it?
26/35
@Heavensshiranui
Amazing, this is becoming increasingly common, and this is the worst it ill ever be!
27/35
@rediminds
Labs used to chase molecules; now molecules chase us. What matters next isn’t speed, it’s having the guardrails to prove a “machine-discovered” material is safe, compliant, and manufacturable at scale. Hats off to John Link and the team for showing that AI acceleration can coexist with real-world validation.
28/35
@ayushjha__
Really cool stuff, We have been using it for materials
29/35
@AntDX316
The ASI-Singularity(Godsend) is the only Global Solution.
30/35
@justinwcaswell
For the record and before Netflix or Disney fukk it up…this is a white male.
31/35
@mikeamark
Using Microsoft discovery, AI is helping to make scientific discoveries.
32/35
@reyreyromonov
33/35
@AGuyNamedDJ_
I’m not cracked enough
34/35
@msakiart
wow impressive
35/35
@HeiligGerh36381
Wow
To post tweets in this format, more info here: https://www.thecoli.com/threads/tips-and-tricks-for-posting-the-coli-megathread.984734/post-52211196
Microsoft Discovery : AI Agents Go From Idea to Synthesized New Material in Hours!
Posted on Tue May 20 14:34:07 2025 UTC
So, they've got these AI agents that are basically designed to turbo-charge scientific R&D. In the demo, they tasked it with finding a new, safer immersion coolant for data centers (like, no "forever chemicals").
The AI:
Scanned all the science.
Figured out a plan.
Even wrote the code and ran simulations on Azure HPC.
Crunched what usually takes YEARS of R&D into basically hours/days.
But here’s the insane part: They didn't just simulate it. They actually WENT AND SYNTHESIZED one of the new coolants the AI came up with!
Then they showed a PC motherboard literally dunked in this new liquid, running Forza Motorsport, and staying perfectly cool without any fans. Mind. Blown.
This feels like a legit step towards AI not just helping with science, but actually doing the discovery and making brand new stuff way faster than humans ever could. Think about this for new drugs, materials, energy... the implications are nuts.
What do you all think? Is this the kind of AI-driven acceleration we've been waiting for to really kick things into high gear?
So, they've got these AI agents that are basically designed to turbo-charge scientific R&D. In the demo, they tasked it with finding a new, safer immersion coolant for data centers (like, no "forever chemicals").
The AI:
Scanned all the science.
Figured out a plan.
Even wrote the code and ran simulations on Azure HPC.
Crunched what usually takes YEARS of R&D into basically hours/days.
But here’s the insane part: They didn't just simulate it. They actually WENT AND SYNTHESIZED one of the new coolants the AI came up with!
Then they showed a PC motherboard literally dunked in this new liquid, running Forza Motorsport, and staying perfectly cool without any fans. Mind. Blown.
This feels like a legit step towards AI not just helping with science, but actually doing the discovery and making brand new stuff way faster than humans ever could. Think about this for new drugs, materials, energy... the implications are nuts.
What do you all think? Is this the kind of AI-driven acceleration we've been waiting for to really kick things into high gear?
1/8
@koltregaskes
Microsoft announces Microsoft Discovery, a science agent that runs experiments via multi-agents, covering chemistry, life sciences, and physics.
2/8
@koltregaskes
3/8
@koltregaskes
4/8
@koltregaskes
5/8
@koltregaskes
6/8
@Fhotec
Interesting to see a cameo from Sam during the keynote.
7/8
@koltregaskes
And Jensen. :-)
8/8
@gilbert_jc
i love seeing ai service healthcare use cases, it really feels like we're going to have so many new innovations in the next decades
if we could be solving all diseases that'd be type 1 type of progress
To post tweets in this format, more info here: https://www.thecoli.com/threads/tips-and-tricks-for-posting-the-coli-megathread.984734/post-52211196
@koltregaskes
Microsoft announces Microsoft Discovery, a science agent that runs experiments via multi-agents, covering chemistry, life sciences, and physics.
2/8
@koltregaskes
3/8
@koltregaskes
4/8
@koltregaskes
5/8
@koltregaskes
6/8
@Fhotec
Interesting to see a cameo from Sam during the keynote.
7/8
@koltregaskes
And Jensen. :-)
8/8
@gilbert_jc
i love seeing ai service healthcare use cases, it really feels like we're going to have so many new innovations in the next decades
if we could be solving all diseases that'd be type 1 type of progress
To post tweets in this format, more info here: https://www.thecoli.com/threads/tips-and-tricks-for-posting-the-coli-megathread.984734/post-52211196
