UK Scientists Worry Vaccines May Not Protect Against South African Coronavirus Variant

[DEAD7]

UK Scientists Worry Vaccines May Not Protect Against South African Coronavirus Variant

Both Britain and South Africa have detected new, more transmissible variants of the COVID-19-causing virus in recent weeks that have driven a surge in cases. British Health Secretary Matt Hancock said on Monday he was now very worried about the variant identified in South Africa. Simon Clarke, an associate professor in cellular microbiology at the University of Reading, said that while both variants had some new features in common, the one found in South Africa "has a number additional mutations ... which are concerning." He said these included more extensive alterations to a key part of the virus known as the spike protein -- which the virus uses to infect human cells -- and "may make the virus less susceptible to the immune response triggered by the vaccines." Lawrence Young, a virologist and professor of molecular oncology at Warwick University, also noted that the South African variant has "multiple spike mutations."

 

[DEAD7]

 

[NkrumahWasRight Is Wrong]

i have a solution

 

[OneManGang]

mRNA vaccines can be made quickly, we just have to re-sequence each variant and tailor the new vaccine. The real problem is getting the roll outs right which a logistical nightmare. Not to mention, gettign people to take just one vaccine is a challenge with the unknown safety profiles, much less if we have to take multiple mRNA vaccines.

 

[ORDER_66]

Told these muthafukkas but they called me crazy about that fukking vaccine..

 

[hashmander]

Told these muthafukkas but they called me crazy about that fukking vaccine..

what are you talking about? what were you called crazy for? someone said this vaccine would work for every variant and you said it wouldn't and they called you crazy?

 

[Hawaiian Punch]

Covid playing chess on us and just said “check”

 

[null]

mRNA vaccines can be made quickly, we just have to re-sequence each variant and tailor the new vaccine. The real problem is getting the roll outs right which a logistical nightmare. Not to mention, gettign people to take just one vaccine is a challenge with the unknown safety profiles, much less if we have to take multiple mRNA vaccines.

How long would it take to run trials on a new mRNA (BioNTech vaccine)?

I don't have the timeline of the first one to hand but wasn't the majority of the time taken up by testing and authorisation?

 

[null]

Told these muthafukkas but they called me crazy about that fukking vaccine..

yeah but you are crazy ...

 

[OneManGang]

How long would it take to run trials on a new mRNA (BioNTech vaccine)?

I don't have the timeline of the first one to hand but wasn't the majority of the time taken up by testing and authorisation?

Technically all that was already done. Any “new” vaccine would just be a new mRNA strand so all that testing was already done and the safety trials are still technically ongoing

 

[ORDER_66]

Told these muthafukkas but they called me crazy about that fukking vaccine..

what are you talking about? what were you called crazy for? someone said this vaccine would work for every variant and you said it wouldn't and they called you crazy?

It is what it is... I'm just gonna say there's gonna be a worse thing that happens and no vaccine gonna help at all... We need a CURE... No half measures...

 

[null]

Technically all that was already done. Any “new” vaccine would just be a new mRNA strand so all that testing was already done and the safety trials are still technically ongoing

You didn't say how long but you seem to be suggesting that new phase trials specifically for the new virus would not be required.

I doubt that for the following reasons at least (off the top of my head) ..

1. If that were the case they could have "tested" the mRNA with any similar corona virus "years ago" and we wouldn't have had to wait from April/May/June through to Dec for the specific tests with SARS Cov II.

2. If it were true we would have to test for duplicate simultaneous vaccinations, as taking more than one vaccine is untested and not allowed under current protocols.

What are your comments on these two points?

Working backwards I think your assumption flies in the face of logic, but hey.. logic, smogic ...

 

[hashmander]

Told these muthafukkas but they called me crazy about that fukking vaccine..


It is what it is... I'm just gonna say there's gonna be a worse thing that happens and no vaccine gonna help at all... We need a CURE... No half measures...

told them what? make sense. the vaccine didn't cause the new strain so I don't know what you were telling people. the only relevance to you claiming you told people is if people said covid-19 wouldn't mutate into other strains and people called you crazy for saying it would.

 

[OneManGang]

You didn't say how long but you seem to be suggesting that new phase trials specifically for the new virus would not be required.

I doubt that for the following reasons at least (off the top of my head) ..

1. If that were the case they could have "tested" the mRNA with any similar corona virus "years ago" and we wouldn't have had to wait from April/May/June through to Dec for the specific tests with SARS Cov II.

2. If it were true we would have to test for duplicate simultaneous vaccinations, as taking more than one vaccine is untested and not allowed under current protocols.

What are your comments on these two points?

Working backwards I think your assumption flies in the face of logic, but hey.. logic, smogic ...

Oh i see. I’m at work so I can’t really go as in depth as I want, but any variant to SARS-COV-2 is still largely the same virus, meaning only slight variations to the genetic code coding for proteins was altered. This means that any new vaccine is just making tweaks to areas they need to make, so there wouldnt have to be any new phase 1 or phase 2 trials, it’s largely the same vaccine. So likely won’t need additional approvals if you’re only getting it for the first time.

Your point about multiple mRNA vaccines at once is a decent one, not sure about that, but they’d most likely have to prove to the FDA efficacy and safety in some capacity for legal reasons.

 

[null]

but any variant to SARS-COV-2 is still largely the same virus

same? antibody binding the same you mean?