Ali was insulted, because he's professionally trained combatant and Wilt is a basketball player
wilt wouldn't even know how to defend himself if Ali attacked him seriously
if Wilt was a trained fighter he would have an advantage over Ali but even then its not guaranteed he would win
I remember on first take Skip Bayless said Hine Wards would beat Sugar Ray Leonard in a fight, and Sugar Ray Leonard was pissed for real because he thought Hine Wards actually said that, and he was ready to find him and beat his ass.