He really just called out the racism in the LGBTQ community.
And their overall hypocrisy. In a previous special he even explained how LGBTQ don't all get along either which is true. It's an ongoing discussion in that community and there are a lot of women who don't rock with transgender people because their insistence on "trans women are women too!" erases the biological functions and experiences that natural born women go through. It's a shared bonding experience for women to talk about puberty, menopause, moments where they wish they were men, child birth, etc. conversations that someone born a male can't understand and chime in on.
He's made it very obvious what he was talking about in this special to the point where he had to stop and tell people to think back to his other shyt where he was explaining it already. He isn't just a comedian, he's a commentator and storyteller. I mean shyt, what does it say that they're more mad at him for this than his jokes that seemed to defend bill cosby? or minimize the shyt Harvey weinstein did?