Coronavirus Thread: Worldwide Pandemic

Kyle C. Barker

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Unless I am missing something, there was a study last week that stated the mRNA vaccines could fight off the COVID19 for years
Pfizer and Moderna Vaccines Likely to Produce Lasting Immunity, Study Finds


The key caveat was in the second paragraph

The findings add to growing evidence that most people immunized with the mRNA vaccines may not need boosters, so long as the virus and its variants do not evolve much beyond their current forms — which is not guaranteed

I personally expected memory b cells to recognize the spike protein years/decades down the line even when antibodies dwindle down. However, as stated, if the spike protein mutates too much and achieves a protien fold that prevents it from binding to the original generated antibodies, then you're gonna need a booster with a modified mRNA sequence to bind with the newly mutated spike protein.

So does Pfizer have a financial interest in selling booster shots? Yes they absolutely do, but at the same time they are selling a product that is actually needed.
 

mastermind

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The key caveat was in the second paragraph

The findings add to growing evidence that most people immunized with the mRNA vaccines may not need boosters, so long as the virus and its variants do not evolve much beyond their current forms — which is not guaranteed

I personally expected memory b cells to recognize the spike protein years/decades down the line even when antibodies dwindle down. However, as stated, if the spike protein mutates too much and achieves a protien fold that prevents it from binding to the original generated antibodies, then you're gonna need a booster with a modified mRNA sequence to bind with the newly mutated spike protein.

So does Pfizer have a financial interest in selling booster shots? Yes they absolutely do, but at the same time they are selling a product that is actually needed.
I am skeptical of the Israel figures, if I am being real.

I don't deny we will need a booster, and I am not saying that it won't happen down the line.

My point is only that we probably don't need it as soon as Pfizer wants it out because the delta varient isn't taking down vaccinated people.
 

Kyle C. Barker

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I am skeptical of the Israel figures, if I am being real.

I don't deny we will need a booster, and I am not saying that it won't happen down the line.

My point is only that we probably don't need it as soon as Pfizer wants it out because the delta varient isn't taking down vaccinated people.


I hear ya.

I put trust in the other peer reviewed U.S. University studies that had the mRNA vaccines remaining extremely effective against the delta strain which contradicted the Israeli study which seemed a little off to me (can't remember what it was about it that seemed off).

An updated mRNA sequence couldn't hurt though, that's all I'm saying :manny:
 

mastermind

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I hear ya.

I put trust in the other peer reviewed U.S. University studies that had the mRNA vaccines remaining extremely effective against the delta strain which contradicted the Israeli study which seemed a little off to me (can't remember what it was about it that seemed off).

An updated mRNA sequence couldn't hurt though, that's all I'm saying :manny:
I agree completely, but not how pfizer is doing it. This seems a straight money grab.
 
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Can someone tell me if it is widely available in NYC? I was just listening to a podcast by the girlfriend of Louis Rossmann a famous youtuber who is helping to get right to repair passed in the country.
She is talking like she is going to be getting the vaccine soon. I just thought that it was widely available around NYC like is is around Northern VA since I was able to get my vaccine back in early May.
Now I am in my 50s and she is much younger but I know that there are a lot of colleges etc requiring students to be vaccinated soon.
Does NYC have a shortage of readily available vaccines?
 
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