I have zero connections to Louisiana and don't pay attention to where famous people are from so this one hard as fukk.
Steamboat Annie
Fats Domino
Lead Belly
Ed Orgeron
P.G.T. Beauregard but I couldn't spell his name right.
That one mayor during Katrina, can't remember his name (Ray Nagin)
That congressman who got hemmed up with the money in his freezer (William J. Jefferson)
I feel like I would have forgotten Louis Armstrong if I hadn't seen him in the thread.
Maybe Bobby Jindal, maybe not.
Random-ass ones I just looked up but had no idea: Bryant Gumbel, Clyde Drexler, John Goodman