All of are good and all can become OP. Exception may be Assault Rifles since they feel the weakest for some parts of the game compared to what Pistols/Sniper/Precision + Stealth, Shotguns, and SMGs can do with their associated perks.
Just pick 2 weapon types and max out their associated trees. You can't really go wrong outside of very early in the game on very hard trying to fight cyberpsychos too quickly.
I was wondering if I was the only one who feels like them Ks ain't hittin like they supposed to(kinda like Borderlands)ARs and SMGs are boring.
I think pure shotguns or handgun builds are the best and most fun with my limited experience. My current build is fully fledge shotgun, though I can also use heavy weapons too. My next build I'm going full sniper and net runner + stealth
During the Day I use Shotgun and a Pistol and this Mega Hammer I got from a Mini Boss and at Night I use a Sniper Rifle and a Silenced Death and Taxes Pistol wit the Katana,I also got Thermal Gorilla Arms....running wit my Night Build made me focus more on Developing the Cool Attributes more


Only reason why I'm not running them is because I'm using shotguns with the launcher combo.