Depression: I'm gonna keep it real for a bit right now.

Audemar

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Kinda caught off guard with this one breh :what: no need to shyt on your breh's before we even get a chance to reach out
I get where he's coming from though. When you tell the average person, especially a male, they'll just tell you to "get over it or just go make some money, have sex, etc." There is also case 2 where people understand for a while, but eventually they too get to that "yeah you just need to get over it" stage as well. It's understandable since as humans we're social conditioned to be happy or at least purse it and you can't really have that happiness around a clinically depressed person.
 
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Depression is a state of mind. If you think you're lonely and unhappy you're going to feel that way.
No it's not.

princ_rm_pet_scan_of_depressed_brain.jpg


I mean, doctors, neuroscientists, and others in the field of medicine and mental health couldn't possibly be joshing us...could they?
Depression’s Chemical Imbalance Explained
By Rick Nauert PhD
~ Less than a minute read
For over three decades, scientists have attributed a chemical imbalance in the brain as the source of major depression. Now, a new study provides an explanation of how this “chemical imbalance” occurs.

Major depression is a disease that impacts approximately 5% of people globally. For over 30 years, scientists believed that monoamines– mood-related chemicals such as serotonin, norepinephrine and dopamine– are low in the brain during major depressive episodes. This is commonly referred to as a “chemical imbalance”. However, no one had ever found a convincing explanation for monoamine loss, until now.


This study by the Canadian-based Centre for Addiction and Mental Health (CAMH) is published in the November Archives of General Psychiatry.

brain_mri.jpg
Dr. Jeffrey Meyer investigated whether brain monoamine oxidase A (MAO-A) — an enzyme that breaks down chemicals like serotonin, norepinephrine and dopamine– was higher in those with untreated depression. The results showed that in major depression MAO-A was significantly higher in every brain region that the scientists investigated. On average, MAO-A was 34% higher.


According to Dr. Meyer, “In major depression, higher levels of MAO-A is the primary process that lowers monoamine levels. Having more MAO-A leads to greater breakdown of key chemicals like serotonin.”


This study by the Canadian-based Centre for Addiction and Mental Health (CAMH) includes a detailed new monoamine model of depression, based upon this work as well as four previous publications from Dr. Meyer and collaborators at CAMH.


Said Dr. Meyer, “A key barrier to making advances in treating depression is a lack of precise disease models. Having disease model is like having a map. Once you have that map you can really begin to understand how an illness like depression works, and offer more targeted and effective treatment.”

A second part of this new model is that monoamine transporters have an important role in removing monoamines away from active sites. Having more of a monoamine transporter is not helpful as it removes more monoamine — for example if one has more serotonin transporter, one would additionally lose more serotonin during depression.


“An important aspect of our advanced monoamine model is that individuals with depression lose chemicals like serotonin and dopamine at different rates based upon transporter density. This helps explain why one person with depression may experience loss of appetite while another may not. And some people have more severe symptoms than others,” said Dr. Meyer.

This advanced monoamine model of depression is a huge step forward in the disease frontier. It brings the study of mental illness closer to the advancements seen in research into physical illness such as cardiac disease, and offers one of the most comprehensive disease models in mental illness.

The next step for researchers will be to investigate why MAO-A levels are raised in the brain and consider prevention strategies. Prevention strategies are critical — according to the World Health Organization, major depression is currently the fourth leading cause of death and disability and is expected to rise to second by the year 2020.

Source: Centre for Addiction and Mental Health

http://psychcentral.com/news/2006/11/09/depressions-chemical-imbalance-explained/398.html
 

Lil Gangsta

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Depression is a state of mind. If you think you're lonely and unhappy you're going to feel that way.
My nikka plz fukk outta here. :what:

Thought patterns are definitely an aspect of depression but the way ur oversimplying and trivializing it is ridiculous and disrespectful. Depression aint no switch dat u can jus turn on and off, its deeper than just a "mindstate".
 

ManxOfxThexYear

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My muthafukkin self
no one understands me. i use to call childline a lot and they did nothing to help me, fukking useless.

Okay all jokes aside, the call center folks can only do so much, there are so many guidelines that in place for their own protection. Most call centers, either have strict policies on suicide and will only take calls if you are suicidal that moment or about to commit that, or see an immediate danger, where the police have to be involved. Others seriously have time restraints that will only stay on the phone with you for a few minutes.

:snoop:

Other call centers, in the states have more ability to talk more and actually try to make a difference. I understand you have called before and have had bad experiences, but there are other lines out there to help. :smile:

Most of these lines are created because there is a lot of people who dont feel understood, and there whole existence is to show your feelings do matter and sometimes, people just need someone to talk to and they just listen, not analyze everything you do and belittle the fukk out of you, but just listen to your feelings.
 
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Kinda caught off guard with this one breh :what: no need to shyt on your breh's before we even get a chance to reach out


But :salute: for the real post. I don't know what you're going through but everybody has their ailments. Keep doing you and feel free to reach out whenever...The Coli got you
Lol...I really wasn't trying to do that...I was just joking for the most part, but I hear it on here whenever the discussion around depression arises.

  • Depression is just a state of mind. If you think that way, you'll be that way.
  • Just suck it up
  • Just get over it...be a man. Men don't get depressed.
  • Depression is for white women
  • Stop being a p*ssy
I mean, if it was just these things, depression (on the clinical level) would be easy to solve...right? But it isn't simply that cut and dry. And we don't really comprehend how our own minds works...there are scientists that have dedicated their lives to studying all of the functions of the brain, and, like the universe, only have a small part of it figured out.
 

scarlxrd

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No it's not.

princ_rm_pet_scan_of_depressed_brain.jpg


I mean, doctors, neuroscientists, and others in the field of medicine and mental health couldn't possibly be joshing us...could they?


http://psychcentral.com/news/2006/11/09/depressions-chemical-imbalance-explained/398.html

shyt's pure ignorance breh.. There's levels to this shyt, being sad/disappointed/whatever feeling you have when shyt doesn't go right at that time isn't the same as clinical depression. When someone says you have to smile through it or change your mindset, it's like you don't know what the hell you're talking about here. Even if that were the case, people with clinical depression cannot do it on their own. :snoop:
 
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I get where he's coming from though. When you tell the average person, especially a male, they'll just tell you to "get over it or just go make some money, have sex, etc." There is also case 2 where people understand for a while, but eventually they too get to that "yeah you just need to get over it" stage as well. It's understandable since as humans we're social conditioned to be happy or at least purse it and you can't really have that happiness around a clinically depressed person.
I've had a friend yell at me to "get professional help and leave me the f*ck alone"...

He also tried to kill himself...so honestly I think depression is something that people suffer from on different levels.
 

TL15

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Lol...I really wasn't trying to do that...I was just joking for the most part, but I hear it on here whenever the discussion around depression arises.

  • Depression is just a state of mind. If you think that way, you'll be that way.
  • Just suck it up
  • Just get over it...be a man. Men don't get depressed.
  • Depression is for white women
  • Stop being a p*ssy
I mean, if it was just these things, depression (on the clinical level) would be easy to solve...right? But it isn't simply that cut and dry. And we don't really comprehend how our own minds works...there are scientists that have dedicated their lives to studying all of the functions of the brain, and, like the universe, only have a small part of it figured out.

Yeah usually simple minded people respond like that. Real talk I read the first post like :ohhh: then :what: :dahell: lol

Gotta take the good with the bad. People who respond negatively are either idiots or :troll:
 

Truth200

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I currently take buproprion. It's helped me out greatly. Also it's helped me out with my ADHD (been dealing with that since the age of seven).

I had ADHD as a kid and did terrible in school in almost didn't graduate High School because of it.

Only reason i went to college was because i got a basketball scholarship but still had to redshirt as a freshman and take remedial classes.

When i got in my 20's i had depression but i think ADHD & depression are underlying symptoms of a bigger illness.
 

TRFG

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No it's not.

princ_rm_pet_scan_of_depressed_brain.jpg


I mean, doctors, neuroscientists, and others in the field of medicine and mental health couldn't possibly be joshing us...could they?


http://psychcentral.com/news/2006/11/09/depressions-chemical-imbalance-explained/398.html

:mjlol:
Clinically depression is far different to the depression most people suffer. I can tell you never did science because what you quoted doesn't even make sense or supports what you're trying to say.

shyt's pure ignorance breh.. There's levels to this shyt, being sad/disappointed/whatever feeling you have when shyt doesn't go right at that time isn't the same as clinical depression. When someone says you have to smile through it or change your mindset, it's like you don't know what the hell you're talking about here. Even if that were the case, people with clinical depression cannot do it on their own. :snoop:

That's what I was trying to say on the first page. The depression OP is referring to is his state of mind, which can be solved by visiting a psychologist NOT a Medical Doctor. In the OP there's no major of Fatigue, Insomnia or hypersomnia, massive weight loss/gain or anhedonia which are symptoms of Clinical depression not depression.
 
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