King
The black man is always targeted.
What the fukk is that supposed to mean?A technological breakthrough, any way you look at it, but Burkina Faso just manufactured its own soap. Baby steps, brothers and sisters.
Dire wolf returns from extinction. Cacs fukking up again
- Thread starter CouldntBeMeTho
- Start date
Secure Da Bag
Veteran
A technological breakthrough, any way you look at it, but Burkina Faso just manufactured its own soap. Baby steps, brothers and sisters.
At least there's a country in Africa producing its own goods and not importing it from abroad. Yeah, baby steps.
Took China 40 years to get where it is. And they had the luxury of no foreign powers interfering domestically.
King
The black man is always targeted.
And the benefit of being one nation, united under one major ethnic group. Had China been in Africa, it would’ve been split up between 50 different countries and thousands of fake made up groups meant to keep the people divided under artificial ethnic conflicts.
Secure Da Bag
Veteran
It is interesting since China has at least 3 ethnic groups not counting Tibet, Mongolia, and I think Uyghurs.
The countries are the made up groups, aren't they? What made up groups are you referring to?
King
The black man is always targeted.
That is why I said majority ethnic group. The situation in China could barely be compared to the complexities of a singular African country.
Hutu and Tutsi, for example, 1+ million dead.
And yes, most of the groups are made up relics colonialism.
Or is colonialism not actually a concept? Do you believe the practices of colonialism and imperialism occurred?
Secure Da Bag
Veteran
I'm asking what do you mean when you say "groups"? You mean countries? Ethnicities? Something else?
King
The black man is always targeted.
I clearly made the differentiation here. Perhaps your “questioning” needs questioning. Have you tried asking yourself why it’s so difficult for you to understand?
this is partly why i believe future humans will be able to live on uninhabitable planets, gene therapy and manipulating the environment. we'll just adapt.
1/25
@BrianRoemmele
This AI can write genomes from scratch.
The Arc Institute with NVIDIA just published Evo-2, the largest AI model for biology, trained on 9.3 trillion DNA base pairs spanning the entire tree of life.
This AI doesn’t just analyze genomes. it creates them.
Link: Manuscript | Arc Institute
2/25
@MarceauFetiveau
The AI revolution in medicine is happening right now.
Diseases we once thought impossible to beat? Their days are numbered.
Get ready to live longer, healthier, and witness the future of medicine unfold.
3/25
@Birdmeister17
I had Grok analyze and summarize this 65 page document so normal people can understand it. We are living in the future. https://grok.com/share/bGVnYWN5_76007630-a88b-4fb8-a71e-12dd4faafc61
4/25
@snarkyslang
This may be a dumb question, but creating genomes from nothing is essentially designing life that doesn't presently exist, is that right?
5/25
@EagleTurd
That's scary actually.
6/25
@NaturallyDragon
Bring back Dragons!
https://video.twimg.com/ext_tw_video/1892322995575934981/pu/vid/avc1/1920x1080/GJ2tuPGw6OXmpNhy.mp4
7/25
@mark74181442
Soon, we will be able to 3-d print it too.
8/25
@Ronan_A1
This is so wild…. The exponential change is mind boggling
[Quoted tweet]
HOLY shyt IT'S HAPPENING
AI can now write genomes from scratch.
Arc Institute an NVIDIA just published Evo-2, the largest AI model for biology, trained on 9.3 trillion DNA base pairs spanning the entire tree of life.
it doesn’t just analyze genomes. it creates them
1/
[media=twitter]1892251343881937090[/media]
9/25
@TheLastDon222
And this is where things get scary. I think we may be entering into a tower of Babel situation.
10/25
@atlasatoshi
11/25
@smbodie3
Scary.
12/25
@neilarmstrongx1
this week is wild, we are all of a sudden in my childhood science fiction distant future. I wouldn't be surprised if Buck Rogers showed up
13/25
@pilot_winds
@robertsepehr you might find this useful.
14/25
@ChrisandOla
Is this a good thing?
15/25
@waldematrix
Great
now they are really going to make cat girls and Werewolves.
16/25
@calledtocnstrct
Now if a cell simulator can be built to model what happens when the
is controlling things... Would be interesting to see what creature develops.
17/25
@CPtte
Wow!
18/25
@CPtte
Just the models of them or are we talking create them in physical form? As an actual strand of DNA?
19/25
@Dusty45Cal
I might read this to my kids tonight.
20/25
@fwchiro
When do I get an uplifted dog that can help with the chores?
21/25
@AltVRat
Plus crisper and
Singularity Escape Velocity
22/25
@Mike___Kilo
You sure that’s a good idea? Just because we can, doesn’t mean we should.
23/25
@D0cCoV
Let it analyze saescov2 genome!
24/25
@MonaLiesbeth
I really don’t think this is a good idea.
25/25
@DaneFreshie
The greater familiarity with biology one has, the more concerning this is.
cks-for-posting-the-coli-megathread.984734/post-52211196[/URL][/SIZE][/B][/COLOR]
@BrianRoemmele
This AI can write genomes from scratch.
The Arc Institute with NVIDIA just published Evo-2, the largest AI model for biology, trained on 9.3 trillion DNA base pairs spanning the entire tree of life.
This AI doesn’t just analyze genomes. it creates them.
Link: Manuscript | Arc Institute
2/25
@MarceauFetiveau
The AI revolution in medicine is happening right now.
Diseases we once thought impossible to beat? Their days are numbered.
Get ready to live longer, healthier, and witness the future of medicine unfold.
3/25
@Birdmeister17
I had Grok analyze and summarize this 65 page document so normal people can understand it. We are living in the future. https://grok.com/share/bGVnYWN5_76007630-a88b-4fb8-a71e-12dd4faafc61
4/25
@snarkyslang
This may be a dumb question, but creating genomes from nothing is essentially designing life that doesn't presently exist, is that right?
5/25
@EagleTurd
That's scary actually.
6/25
@NaturallyDragon
Bring back Dragons!
https://video.twimg.com/ext_tw_video/1892322995575934981/pu/vid/avc1/1920x1080/GJ2tuPGw6OXmpNhy.mp4
7/25
@mark74181442
Soon, we will be able to 3-d print it too.
8/25
@Ronan_A1
This is so wild…. The exponential change is mind boggling
[Quoted tweet]
HOLY shyt IT'S HAPPENING
AI can now write genomes from scratch.
Arc Institute an NVIDIA just published Evo-2, the largest AI model for biology, trained on 9.3 trillion DNA base pairs spanning the entire tree of life.
it doesn’t just analyze genomes. it creates them
1/
[media=twitter]1892251343881937090[/media]
9/25
@TheLastDon222
And this is where things get scary. I think we may be entering into a tower of Babel situation.
10/25
@atlasatoshi
11/25
@smbodie3
Scary.
12/25
@neilarmstrongx1
this week is wild, we are all of a sudden in my childhood science fiction distant future. I wouldn't be surprised if Buck Rogers showed up
13/25
@pilot_winds
@robertsepehr you might find this useful.
14/25
@ChrisandOla
Is this a good thing?
15/25
@waldematrix
Great
now they are really going to make cat girls and Werewolves.16/25
@calledtocnstrct
Now if a cell simulator can be built to model what happens when the
is controlling things... Would be interesting to see what creature develops.17/25
@CPtte
Wow!
18/25
@CPtte
Just the models of them or are we talking create them in physical form? As an actual strand of DNA?
19/25
@Dusty45Cal
I might read this to my kids tonight.
20/25
@fwchiro
When do I get an uplifted dog that can help with the chores?
21/25
@AltVRat
Plus crisper and
Singularity Escape Velocity22/25
@Mike___Kilo
You sure that’s a good idea? Just because we can, doesn’t mean we should.
23/25
@D0cCoV
Let it analyze saescov2 genome!
24/25
@MonaLiesbeth
I really don’t think this is a good idea.
25/25
@DaneFreshie
The greater familiarity with biology one has, the more concerning this is.
cks-for-posting-the-coli-megathread.984734/post-52211196[/URL][/SIZE][/B][/COLOR]
1/34
@IterIntellectus
HOLY shyt IT'S HAPPENING
AI can now write genomes from scratch.
Arc Institute an NVIDIA just published Evo-2, the largest AI model for biology, trained on 9.3 trillion DNA base pairs spanning the entire tree of life.
it doesn’t just analyze genomes. it creates them
1/
2/34
@IterIntellectus
Evo 2 generates mitochondrial, prokaryotic, and eukaryotic sequences at genome-scale
Evo 2 is FULLY OPEN, including model parameters, training code, inference code, and
the OpenGenome2 dataset LMFAO
2/
3/34
@IterIntellectus
think of it as a DNA-focused LLM. instead of text, it generates genomic sequences. it reads and interprets complex DNA, including noncoding regions usually considered jink, generates entire chromosomes and new genomes, and predicts disease-causing mutations, even those not understood
3/
4/34
@IterIntellectus
this is biology hacking
AI is moving beyond describing biology to designing it. this allows for synthetic life engineered from scratch, programmable genomes optimized by AI, potential new gene therapies, and lays the groundwork for whole-cell simulation.
biology is becoming a computational discipline
4/
5/34
@IterIntellectus
it was trained on a dataset of 9.3 trillion base pairs from bacteria, archaea, eukaryotes, and bacteriophages
it processes up to 1 million base pairs in a single context window, covering entire chromosomes. it identifies evolutionary patterns previously unseen by humans
5/
6/34
@IterIntellectus
Evo-2 has demonstrated practical generation abilities, creating synthetic yeast chromosomes, mitochondrial genomes, and minimal bacterial genomes.
this is computational design in action.
6/
7/34
@IterIntellectus
Evo-2 understands noncoding DNA, which regulates gene expression and is involved in many genetic diseases.
it predicts the functional impact of mutations in these regions, achieving state-of-the-art performance on noncoding variant pathogenicity and BRCA1 variant classification.
this could lead to advances in precision medicine
7/
8/34
@IterIntellectus
Evo-2 uses stripedhyena 2, combining convolution and attention mechanisms, not transformers.
it models DNA at multiple scales, capturing long-range interactions, and autonomously learns features like exon-intron boundaries and transcription factor binding sites without human guidance.
it’s not just memorizing
it’s understanding biology.
8/
9/34
@IterIntellectus
Evo-2 predicts whether mutations are harmful or benign without specific training on human disease data.
WHAT
it outperforms specialized models on BRCA1 variants and handles noncoding mutations effectively, suggesting it has learned DNA’s fundamental principles
9/
10/34
@IterIntellectus
Evo-2 generates DNA sequences that influence chromatin accessibility, controlling gene expression.
it has embedded simple Morse code into epigenomic designs as a proof of concept, not a practical application. this shows potential for designing programmable gene circuits.
make me blonde. thank you
10/
11/34
@IterIntellectus
Evo-2 is FULLY OPEN SOURCE, including model parameters, training data, and code.
this will lead to massive widespread innovation in bioengineering, lowering barriers to genome design.
it’s a revolution moment for the field.
the era of biotech is here
11/
12/34
@IterIntellectus
The Arc Institute aims to model entire cells, moving beyond DNA to whole organisms.
this could lead to AI creating new life forms and synthetic biology becoming AI-driven.
the future involves programming life at increasing scales
12/
13/34
@IterIntellectus
three years ago, AI focused on chatbots.
now it generates genomes. soon, it will design complex biological systems. this is a new phase
humans are no longer just studying biology but rewriting its code.
biology’s future is computational. are you prepared?
13/
14/34
@IterIntellectus
Manuscript | Arc Institute
15/34
@boneGPT
if it's possible to use AI to create every possible genome in the latent space of genes, there is a case that humans could have been discovered galaxies away.
Any sufficiently advanced species would know about man long before ever making contact with earth.
16/34
@IterIntellectus
soon
17/34
@kaiotei_
This is insane and a true breakthrough sheesh. just last week i finally had the mind to feed my genome into chatgpt and have it run dozens of analyzations on my SNPs, genomics and AI is big. This is kind of terrifying to me though because I just imagine it creating super extra covid
18/34
@IterIntellectus
or super soldiers lesssgooooo
19/34
@NickADobos
How soon can I can I CRISPR myself with this?
20/34
@IterIntellectus
realistically speaking, safely, 10-15 years
discard safety, 5
21/34
@parakeetnebula
WE LOVE TO SEE IT
22/34
@IterIntellectus
HELL YEAH
23/34
@thatsallfrens
I WANT A GNOME FROM SCRAC
24/34
@IterIntellectus
I WANT BIG PP
25/34
@AISafetyMemes
*taps sign*
[Quoted tweet]
MIT professor and CRISPr gene drive inventor is sounding the alarm:
A 90% lethal virus that infects 50% of humans in 100 days is now possible.
Vaccines will be far too slow.
Extinction cult Aum Shinrikyo went to Africa to produce purified ebola, but, lucky for us, they failed:
Kevin Esvelt: “They bought a uranium mine, they started developing chemical weapons, they started looking for biological weapons. And while there weren’t very many that they had access to at the time, they were able to produce botulinum toxin and they tried to make enough anthrax.
The leader of their bioweapons programme, when they went to Africa, he was hoping that they would find someone who was infected with Ebola so that he could purify the virus and spread it around, so that it would hopefully transmit and kill as many people as possible.”
Omicron infected 50% of Europe in 100 days - vaccines will be much too slow: “Now, imagine something that was released across multiple airports to start with, and you can see how the moonshot vaccine initiatives that hope to get a new vaccine working and approved in 100 days are still going to be much too slow."
90% lethality is possible: “Rabbit calicivirus — it’s more than 90% lethal in adult rabbits. If nature can do that in an animal, that means it’s possible.”
It could spread far faster than natural pandemics because we have air travel.
A new RAND report said: “Previous attempts to weaponise biological agents, such as an attempt by the Japanese Aum Shinrikyo cult to use botulinum toxin in the 1990s, had failed because of a lack of understanding of the bacterium. AI could “swiftly bridge such knowledge gaps”
Bioweapons experts think we might be 1-3 years away from AI-assisted large-scale biological attacks that bring society to its knees.
Open source AI means irreversible proliferation to the Aum Shinrikyos of the world. We’re giving them weapons we can never take back.
[media=twitter]1714384953696211345[/media]
26/34
@AsycLoL
Wtf
27/34
@zeee_media
@threadreaderapp unroll
28/34
@vvdecay
@SorosBruv
29/34
@NI_Intern
Does this mean we're getting Jurassic Park
30/34
@theshadow27
I’m not normally a doomer but this one gives me pause.
An open source version of this means it’s possible to tell it to mix anthrax with Covid. Or worse. CRiSPeR can print any sequence.
What have we done?
31/34
@biotech_bro
Genuinely not overstating how important and transformative it is. You can synthesize organisms that breakdown plastics, and bio-synthetically generate key products and reagents (e.g., Ginkgo on steroids) and maybe even can help terraform planets!!!
32/34
@_anoneng
YAY! Now we can have "life forms" whose genetics are the equivalent of chatgpt slop that barely qualifies as english.
[Quoted tweet]
HOLY shyt IT'S HAPPENING
AI can now write genomes from scratch.
Arc Institute an NVIDIA just published Evo-2, the largest AI model for biology, trained on 9.3 trillion DNA base pairs spanning the entire tree of life.
it doesn’t just analyze genomes. it creates them
1/
[media=twitter]1892251343881937090[/media]
33/34
@craigh64
Now we just need it to design some sort of "perfect organism" that we can use as a weapon!
34/34
@8_O_B
@IterIntellectus
HOLY shyt IT'S HAPPENING
AI can now write genomes from scratch.
Arc Institute an NVIDIA just published Evo-2, the largest AI model for biology, trained on 9.3 trillion DNA base pairs spanning the entire tree of life.
it doesn’t just analyze genomes. it creates them
1/
2/34
@IterIntellectus
Evo 2 generates mitochondrial, prokaryotic, and eukaryotic sequences at genome-scale
Evo 2 is FULLY OPEN, including model parameters, training code, inference code, and
the OpenGenome2 dataset LMFAO
2/
3/34
@IterIntellectus
think of it as a DNA-focused LLM. instead of text, it generates genomic sequences. it reads and interprets complex DNA, including noncoding regions usually considered jink, generates entire chromosomes and new genomes, and predicts disease-causing mutations, even those not understood
3/
4/34
@IterIntellectus
this is biology hacking
AI is moving beyond describing biology to designing it. this allows for synthetic life engineered from scratch, programmable genomes optimized by AI, potential new gene therapies, and lays the groundwork for whole-cell simulation.
biology is becoming a computational discipline
4/
5/34
@IterIntellectus
it was trained on a dataset of 9.3 trillion base pairs from bacteria, archaea, eukaryotes, and bacteriophages
it processes up to 1 million base pairs in a single context window, covering entire chromosomes. it identifies evolutionary patterns previously unseen by humans
5/
6/34
@IterIntellectus
Evo-2 has demonstrated practical generation abilities, creating synthetic yeast chromosomes, mitochondrial genomes, and minimal bacterial genomes.
this is computational design in action.
6/
7/34
@IterIntellectus
Evo-2 understands noncoding DNA, which regulates gene expression and is involved in many genetic diseases.
it predicts the functional impact of mutations in these regions, achieving state-of-the-art performance on noncoding variant pathogenicity and BRCA1 variant classification.
this could lead to advances in precision medicine
7/
8/34
@IterIntellectus
Evo-2 uses stripedhyena 2, combining convolution and attention mechanisms, not transformers.
it models DNA at multiple scales, capturing long-range interactions, and autonomously learns features like exon-intron boundaries and transcription factor binding sites without human guidance.
it’s not just memorizing
it’s understanding biology.
8/
9/34
@IterIntellectus
Evo-2 predicts whether mutations are harmful or benign without specific training on human disease data.
WHAT
it outperforms specialized models on BRCA1 variants and handles noncoding mutations effectively, suggesting it has learned DNA’s fundamental principles
9/
10/34
@IterIntellectus
Evo-2 generates DNA sequences that influence chromatin accessibility, controlling gene expression.
it has embedded simple Morse code into epigenomic designs as a proof of concept, not a practical application. this shows potential for designing programmable gene circuits.
make me blonde. thank you
10/
11/34
@IterIntellectus
Evo-2 is FULLY OPEN SOURCE, including model parameters, training data, and code.
this will lead to massive widespread innovation in bioengineering, lowering barriers to genome design.
it’s a revolution moment for the field.
the era of biotech is here
11/
12/34
@IterIntellectus
The Arc Institute aims to model entire cells, moving beyond DNA to whole organisms.
this could lead to AI creating new life forms and synthetic biology becoming AI-driven.
the future involves programming life at increasing scales
12/
13/34
@IterIntellectus
three years ago, AI focused on chatbots.
now it generates genomes. soon, it will design complex biological systems. this is a new phase
humans are no longer just studying biology but rewriting its code.
biology’s future is computational. are you prepared?
13/
14/34
@IterIntellectus
Manuscript | Arc Institute
15/34
@boneGPT
if it's possible to use AI to create every possible genome in the latent space of genes, there is a case that humans could have been discovered galaxies away.
Any sufficiently advanced species would know about man long before ever making contact with earth.
16/34
@IterIntellectus
soon
17/34
@kaiotei_
This is insane and a true breakthrough sheesh. just last week i finally had the mind to feed my genome into chatgpt and have it run dozens of analyzations on my SNPs, genomics and AI is big. This is kind of terrifying to me though because I just imagine it creating super extra covid
18/34
@IterIntellectus
or super soldiers lesssgooooo
19/34
@NickADobos
How soon can I can I CRISPR myself with this?
20/34
@IterIntellectus
realistically speaking, safely, 10-15 years
discard safety, 5
21/34
@parakeetnebula
WE LOVE TO SEE IT
22/34
@IterIntellectus
HELL YEAH
23/34
@thatsallfrens
I WANT A GNOME FROM SCRAC
24/34
@IterIntellectus
I WANT BIG PP
25/34
@AISafetyMemes
*taps sign*
[Quoted tweet]
MIT professor and CRISPr gene drive inventor is sounding the alarm:
A 90% lethal virus that infects 50% of humans in 100 days is now possible.
Vaccines will be far too slow.
Extinction cult Aum Shinrikyo went to Africa to produce purified ebola, but, lucky for us, they failed:
Kevin Esvelt: “They bought a uranium mine, they started developing chemical weapons, they started looking for biological weapons. And while there weren’t very many that they had access to at the time, they were able to produce botulinum toxin and they tried to make enough anthrax.
The leader of their bioweapons programme, when they went to Africa, he was hoping that they would find someone who was infected with Ebola so that he could purify the virus and spread it around, so that it would hopefully transmit and kill as many people as possible.”
Omicron infected 50% of Europe in 100 days - vaccines will be much too slow: “Now, imagine something that was released across multiple airports to start with, and you can see how the moonshot vaccine initiatives that hope to get a new vaccine working and approved in 100 days are still going to be much too slow."
90% lethality is possible: “Rabbit calicivirus — it’s more than 90% lethal in adult rabbits. If nature can do that in an animal, that means it’s possible.”
It could spread far faster than natural pandemics because we have air travel.
A new RAND report said: “Previous attempts to weaponise biological agents, such as an attempt by the Japanese Aum Shinrikyo cult to use botulinum toxin in the 1990s, had failed because of a lack of understanding of the bacterium. AI could “swiftly bridge such knowledge gaps”
Bioweapons experts think we might be 1-3 years away from AI-assisted large-scale biological attacks that bring society to its knees.
Open source AI means irreversible proliferation to the Aum Shinrikyos of the world. We’re giving them weapons we can never take back.
[media=twitter]1714384953696211345[/media]
26/34
@AsycLoL
Wtf
27/34
@zeee_media
@threadreaderapp unroll
28/34
@vvdecay
@SorosBruv
29/34
@NI_Intern
Does this mean we're getting Jurassic Park
30/34
@theshadow27
I’m not normally a doomer but this one gives me pause.
An open source version of this means it’s possible to tell it to mix anthrax with Covid. Or worse. CRiSPeR can print any sequence.
What have we done?
31/34
@biotech_bro
Genuinely not overstating how important and transformative it is. You can synthesize organisms that breakdown plastics, and bio-synthetically generate key products and reagents (e.g., Ginkgo on steroids) and maybe even can help terraform planets!!!
32/34
@_anoneng
YAY! Now we can have "life forms" whose genetics are the equivalent of chatgpt slop that barely qualifies as english.
[Quoted tweet]
HOLY shyt IT'S HAPPENING
AI can now write genomes from scratch.
Arc Institute an NVIDIA just published Evo-2, the largest AI model for biology, trained on 9.3 trillion DNA base pairs spanning the entire tree of life.
it doesn’t just analyze genomes. it creates them
1/
[media=twitter]1892251343881937090[/media]
33/34
@craigh64
Now we just need it to design some sort of "perfect organism" that we can use as a weapon!
34/34
@8_O_B
Secure Da Bag
Veteran
It's not clear. The fact that this is the 3rd post asking this and you have given a straight answer, proves that.
But yeah, bringing animals back from extinction and their original environments are gone is not a smart thing to do. Last things we need are cross-breeding and a new ecological problem.
Secure Da Bag
Veteran
Consistent steps, you big c00n.A technological breakthrough, any way you look at it, but Burkina Faso just manufactured its own soap. Baby steps, brothers and sisters.
Manufacturing essentials is an important step towards independence.
What this company is doing is why Western civilisation is falling apart at the seams. They haven't brought back the dire wolf. What they did was alter genomes to give a wolf the characteristics of a dire wolf. Then they do what is common practice, market the shyt out of things to make it sexy for investors, knowing full well that they'll never provide anything of substance.
This is why China is no ones friend, and the gullible world likes to think they are..
The Chinese are running around building shyt in foreign nations those locals should be doing themselves, because by doing that China is killing their growth and self suffiency when China itself was allowed to develop at its own pace.
