Both parties split
Democrats will divide into two parties. One will be of big business and corporate interests ( neo liberal free trade, lower corporate tax, socially moderate) that get independents and moderate Republicans and the other will be of blue collar economically liberal populist ideals ( carefully monitored trade, social liberalism, enhanced social programs)
Republicans will split, Moderate Republicans shift to the Centrist party the democrats are in and more reactionary republicans develop a philopshy of nationalism ( carefully monitored free trade, tight immigration reforms, etc)