The game takes place in 2053, in
"post-cyberpocalyptic Neo New York". Twelve years prior, Charles Barkley performed a powerful dunk called a Chaos Dunk at a
basketball game, inadvertently killing most of the people in attendance. As a result, basketball was outlawed and many basketball players were hunted down and killed.
[2]
In 2053, another Chaos Dunk is performed in Manhattan, killing millions. Barkley is blamed for the Chaos Dunk and is hunted by the B-Ball Removal Department, led by
Michael Jordan.
[2][4] Barkley is rescued by another outlaw referred to as the Ultimate Hellbane. Hellbane leads Barkley to the tomb of
LeBron James, revealing that Hellbane's real name is Balthios, the great grandson of James. The ghost of James tells the two to seek the Cyberdwarf, who is hidden in New York's sewers. While searching for the Cyberdwarf, they are joined by a
cybernetic Vince Carter, who has lost his memory. Upon finding Cyberdwarf, the four of them rush to a nearby church, where Barkley's son Hoopz is hiding. In the church, Jordan kills Father
Larry Bird and holds Hoopz hostage. Cyberdwarf, looking at Hoopz, comments that Hoopz may be “The One”; this comment restores Carter's memory. He was killed along with many other basketball stars, but was rebuilt by the terrorist organization B.L.O.O.D.M.O.S.E.S. to kill Hoopz. Carter joins with Jordan, but the two are driven off by Barkley and his party.
Cyberdwarf theorizes that B.L.O.O.D.M.O.S.E.S. used a powerful basketball called the Ultimate B-Ball to perform the recent Chaos Dunk, so they travel to the old
Spalding building to find a rumored extremely powerful basketball. There, they discover that such a ball had been created, dubbed the Hell B-Ball. This ball was so powerful that a janitor who mishandled it inadvertently performed a Chaos Dunk in the building years ago. With the Hell B-Ball in hand, the party seek out B.L.O.O.D.M.O.S.E.S.
They find the B.L.O.O.D.M.O.S.E.S. headquarters on the slave ship Necron 5. After freeing Carter from his programming and defeating Jordan in basketball combat, they find the leader of B.L.O.O.D.M.O.S.E.S., a shadowy version of Barkley created by the Ultimate B-Ball to destroy all life on Earth with a super-powerful Chaos Dunk, then repopulate the earth with Barkley clones. Shadow Barkley is defeated, but machinery on the ship is set to perform the Chaos Dunk without Shadow Barkley. Barkley stays behind as the rest of the party escapes from the Necron 5, then he performs another Chaos Dunk, destroying the ship and saving the earth.
