Ja: went at him first cuz 50 was cool with the nikka who robbed him for his chain
Fat Joe & Jadakiss : He went at Joe & Jadakiss cuz they was on a song with Ja where he was basically throwing shots at 50 & telling him had "a hundred guns, a hundred clips, nikka I'm from New York I got a semi-automatic that spits next time if you talk "
Game:
Cam'ron: Cam let his ego & pride and the fact he was on the radio get the best of him and started talking crazy. 50 was jut responding to Flea
Nas: they shyt go way back to when 50 was running round with Nas & Nas took him off a song he thought would be big. I guess he never let shyt go. Add to the fact he was kicking it with Murder Inc
Diddy: Diddy been a fakkit who try to play with 50's money with the whole Mase deal, they were shaky after that and then Diddy starting putting money behind Ross while they were beefing, all while being around 50 & Floyd, it's only right he go at the fakkit as well
Buck:

Buck was a disloyal ass nikka who was ungrateful
T.i: He definitely went at that nikka for no reason