Nope.
We talking about Coach Pop here
He's still gonna have Kawhi Leonard stalking LeBron on defense. Defensive matchups gonna be like this:
Splitter guarding Miller
Duncan guarding Bosh
Leonard guarding Bron
Green guarding Wade
Parker guarding Neal
All Splitter has to do is close out on Mike Miller who isnt a great passer by any means and doesnt drive, so getting a hand in his face is all that will be needed
On the opposite end though....who is Miller gonna guard? Any perimeter players on the Spurs will cook him and Splitter would dominate him in the post.