I don't feel like it's insignificant at all. Why would it be? We could have been made different, vulnerable without all of the evil and extreme suffering.
I feel like if God exists suffering is a mission of balance. That for all the good and extreme good of this universe, there MUST also be extreme bad and evil. B
It's only significant to us because WE feel the effect of suffering first hand. To ask God, even if we a vulnerable, why must we endure so much pain and suffering, is like asking " Okay I get that this is a quiz, but why does it gotta be so hard for? " We share a world with billions of people in it. People with different ideas and goals. There will be people who are evil , but there are people that will be good to. God let's evil to exist out of the expense of free will. When a challenge or just a bad situation comes, what path do you choose? What you do will be taken note at judgment day.