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Resisting Drug Resistant Pathogens: The Fight Against Candida Auris
Resisting Drug Resistant Pathogens: The Fight Against Candida Auris
As health systems worldwide battle drug-resistant pathogens, Cornell physicians and researchers are fighting against the mysterious and growing threat of Candida auris, a fungus that can cause fatal bloodstream, wound and ear infections.
As of February 28, 2019, the Center for Disease Control confirmed 587 cases of C. auris in the United States, over 300 of which are in New York State. Between 30 percent and 60 percent of people with C. auris have died, although other conditions may have played a role in these deaths.
People at elevated risk for fungal infections,including C. auris, include those with HIV/AIDs, organ transplants or cancer. Additionally, people who have received stem cell transplants, are hospitalized or are taking medications that weaken the immune system are susceptible.
Dr. Matthew McCarthy, who treated C. aurispatients at Weill Medical Center, cautioned against widespread panic about the infection.
“There’s fungi all around us, but they typically only infect people who have weakened immune systems – people who are already sick,” McCarthy told The Sun.
C. auris can be spread from person-to-person or through contact with contaminated equipment or surfaces, although the transmission mechanism is currently unknown. The C.D.C. has expressed concerned about C. auris because it has caused outbreaks in hospitals and nursing homes, is difficult to diagnose with standard laboratory equipment and is often resistant to multiple drugs.
“With fungi, there are just very few antifungal classes (types of antifungal medication) available, so when an organism becomes resistant to a major one, that’s a huge problem,” said Prof. Craig Altier, population medicine and diagnostic sciences, in an interview with The Sun.
The difficulty of developing antifungal drugs is in part due to similarities between human and fungal cells, making finding a drug that kills fungi without being toxic to people difficult.
Resisting Drug Resistant Pathogens: The Fight Against Candida Auris
As health systems worldwide battle drug-resistant pathogens, Cornell physicians and researchers are fighting against the mysterious and growing threat of Candida auris, a fungus that can cause fatal bloodstream, wound and ear infections.
As of February 28, 2019, the Center for Disease Control confirmed 587 cases of C. auris in the United States, over 300 of which are in New York State. Between 30 percent and 60 percent of people with C. auris have died, although other conditions may have played a role in these deaths.
People at elevated risk for fungal infections,including C. auris, include those with HIV/AIDs, organ transplants or cancer. Additionally, people who have received stem cell transplants, are hospitalized or are taking medications that weaken the immune system are susceptible.
Dr. Matthew McCarthy, who treated C. aurispatients at Weill Medical Center, cautioned against widespread panic about the infection.
“There’s fungi all around us, but they typically only infect people who have weakened immune systems – people who are already sick,” McCarthy told The Sun.
C. auris can be spread from person-to-person or through contact with contaminated equipment or surfaces, although the transmission mechanism is currently unknown. The C.D.C. has expressed concerned about C. auris because it has caused outbreaks in hospitals and nursing homes, is difficult to diagnose with standard laboratory equipment and is often resistant to multiple drugs.
“With fungi, there are just very few antifungal classes (types of antifungal medication) available, so when an organism becomes resistant to a major one, that’s a huge problem,” said Prof. Craig Altier, population medicine and diagnostic sciences, in an interview with The Sun.
The difficulty of developing antifungal drugs is in part due to similarities between human and fungal cells, making finding a drug that kills fungi without being toxic to people difficult.
shyt not a joke out here. It pretty much starts off from people not properly washing their entire body