ok, reading your other posts, I will apologize.
It seemed like a question out of left field, because anybody who ups and relocates to a country on another continent would have previously visited and gotten an understanding of laws,rules,customs.
For that reason, I was puzzled at the question.
I have family members and 4 friends (all American citizens) who live in Ghana right now. All but 2 are married to people of Ghanaian descent or birth. If that's a real issue, then they've found ways to circumvent it. There's been a growing community of Western Hemisphere Blacks in Ghana since at least the 1950s, and they have support networks.
Moving and adjusting to different cultures, society, and work environments is hard. People moving from developing countries to the West tend to have more incentive to persevere through the adjustment and obstacles. Person moving from the West to a developing country might have more options and be less willing to deal with obstacles and adjustment.