I see a lot of Run DMC, bone Thugs, Wu Tang, No Limit etc - nobody is denying their talent and contribution to hip hop. But to answer the question? Nobody except Pac (which is currently in production), not even Jay-Z.
When I was learning screenwriting every single time one of the main notes given to me was "you need to have conflict in the story, if there is none, it's boring".
I know some of you guys love 36 Chambers and all that, but outside of the hip hop community who are they? Nobodies. Sure they might be noticeable by face but not on a large scale, where a very significant portion of the US knows about them (even more important if known on an international basis).
NWA was the first music act to EVER have a parental advisory sticker on their cd. Their main song was called "fukk THE POLICE". WHOEVER DARED TO TALK ABOUT THE COPS LIKE THAT, EVER?! Especially on just a large scale. You seen people holding protests over their materials, you had White America's attention (this is very significant with a biopic), there was conflicts all over their image.
8 Mile and Get Rich or Die Tryin' weren't necessarily biopics but portrayed a good portion of Em and 50's lives in the film. Those films were made because their buzz was astronomical at the time. If those movies weren't made I guarantee one on Em would be made on Em in atleast a decade (conflict - difficult upbringing, white rapper, homophobia, record sales, internationally known, abusive towards his wife, etc etc). 50 probably not because his buzz died down but the whole got shot 9 times did wonders for his film then.
A lot of you guys hated Notorious and you know what, aside from the Pac scenario, there was barely any dilemma in Big's life. We don't care about him and Faith Evans relationship, there are cheaters in every film. I haven't seen the James Brown biopic, it came and went. Why? People forgot about him. Sure your grandma plays his records when you go over there, there was a time he sold millions but not much conflict.
The next major biopic musically should be and will be Michael Jackson. Just him being the most famous entertainer on earth and being accused of child molestation charges can be one film and we already know every other conflict he's faced in life (Jackson 5 issues, skin change, etc)