Honestly, my calves are mostly genetic. shyts are gigantic.
That said, I still work the shyt outta them.
I do legs twice a week, and do a couple calf exercises each time.
I've found it important to do a variety of foot angles (toes in/out) to get best results.
My favorite is either burnouts on the leg press machine (usually superset with presses), or crazy dropsets on seated calf raise. Stack 25s till you can't do more than 8 or so....pull the top one off and do till near failure. Repeat until one 25 plate left. (I use 45s, but like I said, my shyts are god given).