COVID-19 Pandemic (Coronavirus)

Dzali OG

Dzali OG

Dz Ali OG...Pay me like you owe me!
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FaTaL said:
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This country needs to be in the streets (masked and gloved up) holding these Mayor's, Governor's, and other public officials accountable!

Listening to the video I posted above is the final straw for me! The leadership in this country has basically decided to let thousands if not millions of people die rather than shut the country completely down, except for food logistics and distribution.

DID YALL HEAR THAT shyt SHE SAID???

That's a horrible death...fukk that!!!
 
23Barrettcity

23Barrettcity

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Slangtonomo said:


Jesus christ for all COVID-19 deniers. She addresses all the "but they're calling everything COVID-19" talk.

It's like its been said, COVID-19 is like AIDS. You may not technically die from COVID-19 but COVID-19 leads to the condition that kills you.
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Here’s the thing most rationale people understood this from the beginning why covid deaths were labeled the way they were . And if they didn’t once explained I hope they did . Everyone else is a conspiracy theorist or being intellectually dishonest . They would use extreme examples like oh someone dies in a car accident but they test positive for covid it’s a covid death ( which I never saw an example of that specific case ) abd any honest mistake due to the lack of available information would be used for supporting bias to their point .
 
eXodus

eXodus

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eXodus said:
Oh shyt! So if this is the case, it isn’t actually an antibody dependent enhancement response to the older coronaviruses like in a dengue infections or the MERS study with rabbits but actually the same as the H2N2/H3N2 outbreaks in 50s and 60s where exposure to similar influenza strains offered protection!

I would see that as good news .. I wonder how sophisticated antibody tests for other common coronaviruses are?
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Very, very interesting study posted in Nature this week! giving more credence to this possible explanation as to why some people have a tough go with the virus and others have a mild case or are asymptomatic. BUT the positive immune response is not tied to antibodies but rather T-Cell response!

https://www.nature.com/articles/s41586-020-2550-z_reference.pdf

SARS-CoV-2-specific T cell immunity in cases of COVID-19 and SARS, and uninfected controls


The distribution of these viruses in different animal species might result in periodic human contact inducing ORF-1-specific T cells with cross-reactive ability against SARS-CoV-2.
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These latter two T cell specificities were particularly intriguing since the homology between the two protein regions of SARS-CoV-1/2 and other “common cold” coronaviruses (OC43, HKU1 NL63 and 229E) was minimal (Fig. 4e), especially for the CD8 peptide epitope. Indeed, the low homology peptides covering the sequences of “common cold” coronaviruses failed to stimulate PBMC of the NSP7 36-50 responsive individuals (Extended Data Fig. 8c). Even though we cannot exclude that some SARS-CoV-2 reactive T cells might be naïve or induced by completely unrelated pathogens, this finding suggests that other
presently unknown coronaviruses, possibly of animal origin, might induce cross-reactive SARS-CoV-2 T cells in the general population.
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Essentially, SARS-1, and Sars-Cov-2 have identical NSP7 and 13 proteins which can be found in betacoronaviruses that cause milder respiratory infections/common colds (OC43 and HKU1) or more likely other presently unknown coronaviruses that cause similar mild infections.

During an immune response to Sars-Cov-2, a person who had been exposed to one of the endemic or to a scientifically unknown betacoronavirus, had previously “informed” T-cells which would recognise and target these familiar proteins and effectively mount a prompt and measured defense. T-cells remember this portion of the virus from its sister virus that you were exposed to and allows the adaptive immune system to effectively target it.

As opposed to antibodies, T-cell memory would be the key to a long lasting/strong immune response and in this theory a prior exposure to these specific betacoronaviruses might be the reason some people have an “immunity” of sorts.


On the other hand when the cytotoxic T-cells don’t recognise the pathogen off the bat, they overcompensate and go ham on your system, causing a cytokine storm while failing to effectively eliminate the virus
:francis:
 
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Jesus H. Christ

Jesus H. Christ

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ALonelyDad said:
EdE4M4JWoAExeJJ






:mjlol:
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:mjgrin: well isn't that just tough?
 
No Sleep

No Sleep

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I had a dumb ass yesterday tell me that his friend girlfriend called her doctor to get tested for covid one morning because she wasn't feeling well, she missed the appointment that she made because she went back to sleep and over slept it. So five days later she got a call that she has tested positive for Covid-19 without even taking the test. My question was why didn't she ask for a letter in writing or even record the nurse telling her that knowing that she didn't take the test. His reply was "I don't think they would lie"... "They" are Trump supporters by the way.

These fukkers will tell the dumbest lies without even thinking about what they are saying.

When the folk who I know that had it and/or been around someone that has it got tested they had to go to certain sites with referrals to get the test because of people they'd been around that had it. It wasn't just call your doctors office and they can test you for it like the dam flu.
 
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Bigblackted4

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eXodus said:
Very, very interesting study posted in Nature this week! giving more credence to this possible explanation as to why some people have a tough go with the virus and others have a mild case or are asymptomatic. BUT the positive immune response is not tied to antibodies but rather T-Cell response!

https://www.nature.com/articles/s41586-020-2550-z_reference.pdf

SARS-CoV-2-specific T cell immunity in cases of COVID-19 and SARS, and uninfected controls







Essentially, SARS-1, and Sars-Cov-2 have identical NSP7 and 13 proteins which can be found in the betacoronavirus that cause milder respiratory infections/common colds (OC43 and HKU1) or more likely other presently unknown coronaviruses that cause similar mild infections.

During an immune response to Sars-Cov-2, a person who had been exposed to one of the endemic or scientifically unknown betacoronaviruses, had previously “informed” T-cells which would recognise and target these familiar proteins and effectively mount a prompt and measured defense. T-cells remember this portion of the virus from its sister virus that you were exposed to and allows the adaptive immune system to effectively target it.

As opposed to antibodies, T-cell memory would be the key to a long lasting/strong immune response and in this theory and prior exposure to these specific betacoronaviruses might be the reason some people have an “immunity” of sorts.


On the other hand when the cytotoxic T-cells don’t recognise the pathogen off the bat, they overcompensate and go ham on your system, causing a cytokine storm while failing to effectively eliminate the virus
:francis:
Click to expand...
Thanks for the explanation makes sense but kind of crazy
 
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