Growing up...yeah, not really. Only on rare cases did I come across any females that could even casually be considered "good" at games. My wife can play platformers moderately well enough tho, but of course, choosing to rarely ever play them, in favor of playing all the dumb, non-game "games" out there that are on cell phones and such. Even then, she rarely plays them.
At my local fighting game scene, there's only 1 girl that consistently shows up to tourneys and she's...ok. She can actually do combos, moves and has some sort of method of gameplan going on, but she's pretty free to me. There's been about 2-3 others that I've seen come before and actually play on occasion and they were a few steps below her skill level. At best, at least they're better than like those celebrities that was on the e-league a few weeks ago, Lupe included.