Ebola virus in Guinea ‘most aggressive, near totally fatal’

[Black White Sox Hat]

Lady at my work been coughing all day.I keep messing with her saying she's got ebola and going to give it to us all.She getting mad.

 

[Spidey Man]

) - Three top secret, experimental vials stored at subzero temperatures were flown into Liberia last week in a last-ditch effort to save two American missionary workers who had contracted Ebola, according to a source familiar with details of the treatment.

On July 22, Dr. Kent Brantly woke up feeling feverish. Fearing the worst, Brantly immediately isolated himself. Nancy Writebol's symptoms started three days later. A rapid field blood test confirmed the infection in both of them after they had become ill with fever, vomiting and diarrhea.

It's believed both Brantly and Writebol, who worked with the aid organization Samaritan's Purse, contracted Ebola from another health care worker at their hospital in Liberia, although the official Centers for Disease Control and Prevention case investigation has yet to be released.

A representative from the National Institutes of Health contacted Samaritan's Purse in Liberia and offered the experimental treatment, known as ZMapp, for the two patients, according to the source.

The drug was developed by the biotech firm Mapp Biopharmaceutical Inc. The patients were told that this treatment had never been tried before in a human being but had shown promise in small experiments with monkeys.

According to company documents, four monkeys infected with Ebola survived after being given the therapy within 24 hours after infection. Two of four additional monkeys that started therapy within 48 hours after infection also survived. One monkey that was not treated died within five days of exposure to the virus.

Brantly and Writebol were aware of the risk of taking a new, little understood treatment; informed consent was obtained from both Americans, according to two sources familiar with the care of the missionary workers. In the monkeys, the experimental serum had been given within 48 hours of infection. Brantly didn't receive it until he'd been sick for nine days.

The medicine is a three-mouse monoclonal antibody, meaning that mice were exposed to fragments of the Ebola virus and then the antibodies generated within the mice's blood were harvested to create the medicine. It works by preventing the virus from entering and infecting new cells.

The Ebola virus causes viral hemorrhagic fever, which refers to a group of viruses that affect multiple organ systems in the body and are often accompanied by bleeding.

Early symptoms include sudden onset of fever, weakness, muscle pain, headaches and a sore throat. They later progress to vomiting, diarrhea, impaired kidney and liver function -- and sometimes internal and external bleeding.

The ZMapp vials reached the hospital in Liberia where Brantly and Writebol were being treated Thursday morning. Doctors were instructed to allow the vials to thaw naturally without any additional heat. It was expected that it would be eight to 10 hours before the medicine could be given, according to a source familiar with the process.

Brantly asked that Writebol be given the first dose because he was younger and he thought he had a better chance of fighting it, and she agreed. However, as the first vial was still thawing, Brantly's condition took a sudden turn for the worse.

Brantly began to deteriorate and developed labored breathing. He told his doctors he thought he was dying, according to a source with firsthand knowledge of the situation.

Knowing his dose was still frozen, Brantly asked if he could have Writebol's now-thawed medication. It was brought to his room and administered through an IV. Within an hour of receiving the medication, Brantly's condition dramatically improved. He began breathing easier; the rash over his trunk faded away. One of his doctors described the events as "miraculous."

By the next morning, Brantly was able to take a shower on his own before getting on a specially designed Gulfstream air ambulance jet to be evacuated to the United States.

Writebol also received a vial of the medication. Her response was not as remarkable, according to sources familiar with the treatment. However, doctors on Sunday administered Writebol a second dose of the medication, which resulted in significant improvement.

She was stable enough to be evacuated back to the United States and is expected to arrive before noon Tuesday.

ZMapp has not been approved for human use, and has not even gone through the clinical trial process, which is standard to prove the safety and efficacy of a medication. The process by which the medication was made available to Brantly and Writebol is highly unusual. It may have fallen under the U.S. Food and Drug Administration's "compassionate use" regulation, which allows access to investigational drugs outside clinical trials.

Getting approval for compassionate use is often long and laborious, but in the case of Brantly and Writebol, they received the medication within seven to 10 days of their exposure to the Ebola virus.

On July 30, the Defense Threat Reduction Agency, an arm of the military responsible for any chemical, biological, radiological, nuclear and high-yield explosive threats, allotted additional funding to MAPP Biopharmaceutical due to "promising results."

http://www.cnn.com/2014/08/04/health/experimental-ebola-serum/index.html?c=homepage-t&page=0

Yeah science. It's nice being an American at times

 

[Digga38]

Lady at my work been coughing all day.I keep messing with her saying she's got ebola and going to give it to us all.She getting mad.

You're already dead my friend

 

[newarkhiphop]

Brehs I just thought of something, if there is NO cure for this, why they bring these two people here for?

 

[Hydroking23]

A Nigerian doctor has contracted Ebola after treating an American who died there last month, the Nigerian health ministry said Monday.

The doctor treated Patrick Sawyer, who contracted Ebola while working in Liberia, then collapsed after he got off a plane to Nigeria and died July 25. Sawyer, 40, was a naturalized American citizen who lived in Minneapolis and was working as a consultant for the Liberian finance ministry.

Sawyer was traveling to Nigeria on business and grew ill on the plane. Nigerian authorities took him into isolation but did not quarantine his fellow passengers, and they have insisted that the risk of additional cases was minimal. The World Health Organization has confirmed three probable Ebola cases in Nigeria and one suspected case. WHO has confirmed more than 1,400 in all in West Africa.

http://www.nbcnews.com/storyline/eb...er-treating-american-who-died-nigeria-n171946

This doesn't look good for my Nigerian people.....

 

[2Quik4UHoes]

Goddamn it.

 

[Hiphoplives4eva]

 

[Blackking]

This is about to get crazy... my girl told me this shyt would pop off like a month ago, and I figured she was just bEing smartdumb

 

[Robert California]

Patient Zero??

 

[Hydroking23]

Yeah its not looking good for 9ja, first Boko Haram, now Ebola, and we still got the fukkery of an election to worry about in a few months. Are the health authorities even doing anything? What is Goodluck saying about this??

 

[TMNT4000]

 

[Goombreh]

shyt is about to get real brehs.

 

[wire28]

fear mongering

 

[无名的]

I'm so tired of you fukking conspiratorial retards.

 

[tru_m.a.c]

@BarNone can we make this the official ebola thread

we don't need 50-11 threads about the ebola like muhfukkas cared about this shyt in March/April