Depends, what area you hitting? If your doing something near wrigleyville to Lincoln Park, you are good. Even wicker and SOME parts of logan square (Shout's out to the boiler room). You run into no riff raff, but you gotta deal with cornballs and hipsters. On the other hand, some of them hipster chicks


. If you are going downtown, unless you start throwing elbows at random folks, you should be fine.
Just be mindful of northside dive bars and how you are getting home. Nothing bad should happen to you, but if you are in say Uptown and drunk as shyt, you might get dropped by a bum. All the crazies and crazy thugs are up there in the evenings, posted out at 2am like its 2pm.