Honestly, looking at the logistics: Israel is 2000km away from the closest point to Iran. That’s only going one way.
The F-35 has a max range of 2000km (that may be with external tanks which hinders its stealth), that’s with no combat and they only have 40 of them. Each F-35 will need to refuel in air to make that round trip, that’s basically for sure.
Logistically, that’s a tough run with a lot of refueling and constant reloading. Not to mention you can’t quickly deploy them so fast back-to-back, you need thorough maintenance because you don’t want to crash one near enemy territory. Those maintenance crews are additionally going to be exhausted, after a single week. It’s not a car, those things need a monstrous amount of inspection, diagnostics, checking it’s coating thoroughly, etc. It’s 140+ hours of labor per crew for a single F-35 flying that mission. Longer if their air base has been attacked.
Not quite sure I buy the “air superiority over the region” claim (at least not over Iran) or if it really even means that much at this point because most time is spent making the flight. I’m sure any refueling planes can additionally be targeted because they’re not stealthy.
Running this on A.I, the rating of difficulty it gives these missions is a solid 8.5-9.5/10 for the IAF and that includes with F-35’s. This is nowhere like Ukraine and Russia distance. They got to fly over four countries to strike a target in Iran, then fly all the way back.
I don’t know why more people aren’t bringing that up. It may seem like a straight-forward mission, but implementation and logistics are ugly af.