hell to the naw....especially since Mandalay has the Liquid club there now, which is one of the more poppin night spots on the strip. The south area of the strip has really picked up with Hakkasan and Liquid...it used to be a dead area up until last year.
Thats the good part, the bad part is that you are going on one of the five biggest vegas travel days of the year. On days like Indy day, they charge top dollar for everything because Vegas is crawling with ballers and groupies. Things like entry and such are quite congested and competitive. Bottom line is that you need to have your bread right to have a good time, because money talks during labor day, new years, indy day, memorial day, holloween, etc. Even shtty clubs charge top dollar during the holidays ---- even for women.