If it's a last second change, than no player is breaking it up - except for fouling. If a player (I guess in this context it's usually a big man) has the jump on the closest defender than i
t's over. No elite rim protector (other than Draymond) has the smarts or reaction time to defuse a lob if a big man is already in the motion of going up for it. If Draymond is "vulnerable" to last second change lobs than every other player is too. And in that same frame, you could apply that to every single basketball activity that a defender is "vulnerable" to.
It's funny how you even minimized it to situational lobs, but than praised him like no other for reading/anticipating, identifying styles and defusing them before the player even has the chance to catch the ball. If you believe that he can do all that, than I don't see how you can believe he's vulenerable to lobs at all.