50's success doesn't have anything to do with him being from NY.
Thing is, a lot of artists have always had an inferiority complex with NY, when regional consideration really doesn't have anything to do with success in the music business after the late 90's. Soundscan actually showed that 50 was selling a lot more records in other states, rather than in NY. NY has always been the bootleg capitol. It's the fans in other states who were really going out and buying those retail copies back then. 50 pointed that out a few times. He wasn't new to anyone in NY. Outside of NYC, people went crazy for him.
Nelly dropped at the perfect time, because in 2000, the kind of pop-rap music he was making was a lot more acceptable, than it would've been before or even just a few years after that. That's why he wasn't able to pop anymore just 3-4 years later. Comparing Nelly to 50 is seriously apples and oranges. 50 came in making the same kinda shyt he made on the mixtape circuit, but just with a huge corporate machine behind him. Nelly came in making poppy rap songs that had catchy highly-accessible lyrics that catered to radio and Top 40. These dudes are very different kinds of artists. I think Tip is tight because people were online shytting on his catalogue against Fif's. He's mad now, and try’na diss Nelly and 50 in the process.